I hope that some day the practice of producing cowpox in human beings will spread over the world - when that day comes, there will be no more smallpox.
-Dr. Edward Jenner
“When once all the adults susceptible of the infection should either have received it or be dead without suffering from it, the very want of variolous matter would put a stop to both the natural and artificial smallpox. Inoculation would then cease to be necessary, and therefore be laid aside.”
— Matthew Maty, The Advantages of Early Inoculation